Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
28/08/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
DUDA, N. C. B.; VALLE, S. de F.; MATHEUS, J. P.; ANGELI, N. C.; VIEIRA, L. C.; OLIVEIRA, L. O.; SONNE, L.; González, F. H. D. |
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Afiliação: |
Naila C. B. Duda, Departamento de Patologia Clínica Veterinária / Faculdade de Veterinária / Universidade Federal do Rio Grande do Sul - UFRGS; Stella de F. Valle, Departamento de Patologia Clínica Veterinária / Faculdade de Veterinária / Universidade Federal do Rio Grande do Sul - UFRGS; Juliana P. Matheus, Departamento de Patologia Clínica Veterinária / Faculdade de Veterinária / Universidade Federal do Rio Grande do Sul - UFRGS; Natália C. Angeli, Departamento de Patologia Clínica Veterinária / Faculdade de Veterinária / Universidade Federal do Rio Grande do Sul - UFRGS; Luciane C. Vieira, Setor de Oncologia Veterinária / Faculdade de Veterinária / UFRGS; Luciana O. Oliveira, Setor de Oncologia Veterinária / Faculdade de Veterinária / UFRGS; Luciana Sonne, Setor de Patologia Veterinária /Faculdade de Veterinária /UFRGS; Departamento de Patologia Clínica Veterinária / Faculdade de Veterinária / Universidade Federal do Rio Grande do Sul - UFRGS. |
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Título: |
Paraneoplastic hematological, biochemical, and hemostatic abnormalities in female dogs with mammary neoplasms. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 5, p. 479-484, maio 2017. |
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Idioma: |
Inglês |
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Notas: |
Título em português: Anormalidades hematológicas, bioquímicas e hemostáticas de origem paraneoplásica em fêmeas caninas com neoplasia mamária. |
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Conteúdo: |
Paraneoplastic laboratory abnormalities are identified in several types of cancers in dogs and cats. In veterinary medicine, particularly in mammary cancer, there are few studies that correlate abnormal laboratory findings with tumor type and staging. The aim of this study was to evaluate hematological, biochemical, and hemostatic abnormalities and correlate them with mammary tumor staging in female dogs with mammary cancer. Blood samples from 24 female dogs were evaluated, and the hematological, biochemical, and hemostatic parameters were correlated with tumor staging obtained by physical examination, imaging exams, and histopathological surgical biopsies. The groups were organized according to tumor staging: group 1 (stages I and II), group 2 (stage III), and group 3 (stages IV and V). Anemia, neutrophilic leukocytosis, monocytosis, eosinophilia, thrombocytosis, hypoalbuminemia, hypocalcemia, hypoglycemia, and low blood urea were observed. The variables MCHC, TPP, and RDW were correlated with tumor staging with no clinical relevance. Thrombin time and fibrinogen were significant between the groups in the coagulation test, being associated with tumor staging. The findings suggest influence of the proinflammatory cytokines released during tumor growth. |
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Palavras-Chave: |
Estadiamento tumoral mamário; Hiperfibrinogenemia; Hyperfibrinogenemia; Laboratory parameters; Mammary tumor staging; Parâmetro laboratorial; Paraneoplastic syndromes; Síndrome paraneoplásica. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/163069/1/Paraneoplastic-hematological.pdf
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Marc: |
LEADER 02416naa a2200313 a 4500
001 2074523
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aDUDA, N. C. B.
245 $aParaneoplastic hematological, biochemical, and hemostatic abnormalities in female dogs with mammary neoplasms.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Anormalidades hematológicas, bioquímicas e hemostáticas de origem paraneoplásica em fêmeas caninas com neoplasia mamária.
520 $aParaneoplastic laboratory abnormalities are identified in several types of cancers in dogs and cats. In veterinary medicine, particularly in mammary cancer, there are few studies that correlate abnormal laboratory findings with tumor type and staging. The aim of this study was to evaluate hematological, biochemical, and hemostatic abnormalities and correlate them with mammary tumor staging in female dogs with mammary cancer. Blood samples from 24 female dogs were evaluated, and the hematological, biochemical, and hemostatic parameters were correlated with tumor staging obtained by physical examination, imaging exams, and histopathological surgical biopsies. The groups were organized according to tumor staging: group 1 (stages I and II), group 2 (stage III), and group 3 (stages IV and V). Anemia, neutrophilic leukocytosis, monocytosis, eosinophilia, thrombocytosis, hypoalbuminemia, hypocalcemia, hypoglycemia, and low blood urea were observed. The variables MCHC, TPP, and RDW were correlated with tumor staging with no clinical relevance. Thrombin time and fibrinogen were significant between the groups in the coagulation test, being associated with tumor staging. The findings suggest influence of the proinflammatory cytokines released during tumor growth.
653 $aEstadiamento tumoral mamário
653 $aHiperfibrinogenemia
653 $aHyperfibrinogenemia
653 $aLaboratory parameters
653 $aMammary tumor staging
653 $aParâmetro laboratorial
653 $aParaneoplastic syndromes
653 $aSíndrome paraneoplásica
700 1 $aVALLE, S. de F.
700 1 $aMATHEUS, J. P.
700 1 $aANGELI, N. C.
700 1 $aVIEIRA, L. C.
700 1 $aOLIVEIRA, L. O.
700 1 $aSONNE, L.
700 1 $aGonzález, F. H. D.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 5, p. 479-484, maio 2017.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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